A Case of Anaphylaxis to Measles Vaccination in an Infant with Cow's Milk Allergy

Pediatric Allergy, Immunology, and Pulmonology
Sevgi SipahiZeynep Tamay

Abstract

Background: Cow's milk is one of the most common of the foods that cause food allergies in children. Here, we present a 10-month-old male who was diagnosed with having an allergy to cow's milk and who developed an anaphylactic reaction after being recently vaccinated with a measles vaccine. Case: The patient had been diagnosed with atopic dermatitis and cow's milk allergy at 40 days old after a rash appeared on his face and arms while exclusively breastfeeding. At 9 months, on his routine welfare outpatient appointment, he developed a facial rash and swelling, wheezing, difficulty breathing, and cyanosis within 10 min of having his first measles vaccination (M-VAC®; Serum Institute of India, Hadapsar, Pune, India). After an allergy evaluation and a physical examination that showed that he was otherwise healthy, he was diagnosed with an allergy to cow's milk, which was then eliminated from his diet. Laboratory evaluations were as follows: serum immunoglobulin E (IgE) to cow's milk: 36.2 kU/L, α-lactalbumin: 9.39 kU/L, β-lactoglobulin: 8.74 kU/L, casein: 34.2 kU/L, latex-specific (sp)IgE: 0.10 kU/L, gelatin spIgE: <0.35 kU/L (normal levels <0.35 kU/L; Pharmacia, Uppsala, Sweden). Results revealed lactalbumin hydrolysate as one...Continue Reading

References

Sep 24, 1994·BMJ : British Medical Journal·C CaffarelliG F Zambelloni
Dec 22, 1998·Allergy·J M Wal
Feb 7, 2001·Pediatrics·A PatjaH Peltola
Nov 29, 2002·Pediatrics·Vitali PoolUNKNOWN VAERS Team. US Vaccine Adverse Event Reporting System
Oct 3, 2003·Pediatrics·Kari BohlkeUNKNOWN Vaccine Safety Datalink Team
Oct 23, 2008·Archives of Disease in Childhood·M Erlewyn-LajeunesseA Emond
Dec 8, 2010·The Journal of Allergy and Clinical Immunology·Alessandro FiocchiRichard F Lockey
Jan 18, 2011·The Journal of Allergy and Clinical Immunology·Scott H Sicherer
Jun 1, 2011·The Journal of Allergy and Clinical Immunology·Jacob D KattanScott H Sicherer
Jan 26, 2012·Archives of Disease in Childhood·Michel Erlewyn-LajeunesseAdam Finn
Jan 22, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C A S ParisiG H Docena
Oct 18, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Jean-Christoph CaubetPhilippe A Eigenmann
Apr 9, 2015·Clinical and Translational Medicine·Fabrizio FranceschiniCarlo Caffarelli
Sep 30, 2016·The World Allergy Organization Journal·Stephen C DreskinLanny J Rosenwasser
Feb 22, 2017·Vaccine·Rajiva de SilvaGathsaurie Neelika Malavige

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Related Concepts

Related Feeds

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.