A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis

Case Reports in Dermatology
Xiaoping LiuMingyuan Xu

Abstract

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multinucleated giant cells. The pathogenesis of the disease is unclear. We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period.

References

Jul 1, 1995·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·B HermesB M Czarnetzki
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Jun 10, 2016·International Journal of STD & AIDS·Antonio Di BiagioClaudio Viscoli

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Citations

Dec 11, 2020·The American Journal of Dermatopathology·Esther HenebengChristopher DiMarco

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Methods Mentioned

BETA
biopsy

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