A case of atrophoderma of Pasini and Pierini: analysis of glycosaminoglycan of the lesional skin

The Journal of Dermatology
S Tajima, K Sakuraoka

Abstract

We report a case of atrophoderma of Pasini and Pierini. We determined the glycosaminoglycan content in the involved skin. Dermatan sulfate content in the involved skin (1.88 micrograms uronic acid/mg dry skin) was greater than that in the uninvolved skin (1.05 micrograms uronic acid/mg dry skin). No significant differences in hyaluronic acid, chondroitin sulfate or heparan sulfate content between involved and uninvolved skin were observed. These results suggest that abnormal metabolism of dermatan sulfate may be involved in the pathogenesis of atrophoderma; this pattern has been observed in systemic or localized scleroderma.

References

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Jan 1, 1985·Connective Tissue Research·R MøllerT Ammitzbøll
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Citations

Apr 29, 2005·Journal of the American Academy of Dermatology·Gina C Ang, Jason B Lee
Sep 1, 1996·The Journal of Dermatology·R P Braun, J H Saurat
Aug 3, 2005·Pediatric Dermatology·Gina AngJason B Lee
Sep 30, 2000·Clinical and Experimental Dermatology·Y YokoyamaO Ishikawa
Jun 19, 2013·Journal of Sex & Marital Therapy·Scott A Adams
Mar 9, 2019·Clinical Case Reports·Anastasiya MuntyanuAbdulhadi Jfri

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