A case of autoimmune gastritis with fundic gland polyp-like pseudopolyps presenting with nodular enterochromaffin-like cell hyperplasia.

Clinical Journal of Gastroenterology
Tohru KoteraKen Haruma

Abstract

Pseudopolyps, a type of remnant oxyntic mucosa on a background of corpus-restricted mucosal atrophy, are a characteristic endoscopic finding in autoimmune gastritis (AIG). Linear or nodular enterochromaffin-like (ECL) cell hyperplasia, a characteristic histopathological finding of AIG, is not generally found in pseudopolyps. We report a case of AIG with fundic gland polyp (FGP)-like pseudopolyps containing nodular ECL cell hyperplasia. A 64-year-old man underwent esophagogastroduodenoscopy, which revealed atrophic changes limited to the corpus, with a normal antrum. The greater curvature was less atrophic than the lesser curvature. Sessile or semipedunculated polypoid lesions were observed on the greater curvature and on the anterior and posterior walls of the corpus. The polypoid lesions resembled FGPs, although some were larger than FGPs generally are. Histologically, non-atrophic fundic glands with parietal cell pseudohypertrophy were observed in the upper regions of the polypoid lesions. By contrast, at the base of the lesions, where linear and nodular ECL cell hyperplasia was identified by immunohistochemical staining, destruction of fundic glands with lymphocytic infiltration, loss of parietal cells, and pseudopyloric met...Continue Reading

References

May 1, 1973·The American Journal of Digestive Diseases·R G Strickland, I R Mackay
Feb 19, 2002·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Michael TorbensonTsung-Teh Wu
Jan 28, 2003·The American Journal of Surgical Pathology·Alyssa M KrasinskasEmma E Furth
Oct 27, 2010·The American Journal of Surgical Pathology·Jason Y ParkElizabeth Montgomery
Dec 4, 2012·Gastrointestinal Endoscopy·Jason Y ParkRoopa Vemulapalli
Jun 19, 2013·Nature Reviews. Gastroenterology & Hepatology·William L NeumannRobert M Genta
Nov 18, 2015·World Journal of Gastroenterology : WJG·Irene CoatiMassimo Rugge
Jul 1, 2017·Clinical Journal of Gastroenterology·Tsutomu TakedaSumio Watanabe
May 16, 2019·Histopathology·Masahide FukudaRyoji Kushima
Aug 2, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Shuichi TeraoKen Haruma

❮ Previous
Next ❯

Citations

Oct 22, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Tomoari KamadaKen Haruma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

World Journal of Gastroenterology : WJG
Dimitrios S PolitisDimitrios K Christodoulou
Clinical Journal of Gastroenterology
Maiko KishinoKatsutoshi Tokushige
Journal of Pediatric Gastroenterology and Nutrition
Tania MitsinikosVrinda Bhardwaj
Journal of Pediatric Gastroenterology and Nutrition
Tania MitsinikosVrinda Bhardwaj
© 2021 Meta ULC. All rights reserved