PMID: 8606041Jun 1, 1995Paper

A case of autoimmune hemolytic anemia induced by IFN-beta therapy for type-C chronic hepatitis

Fukushima Journal of Medical Science
Y KazutaR Kasukawa

Abstract

A 51-year old woman who had type-C chronic hepatitis developed autoimmune hemolytic anemia after 4 weeks treatment with a total 48 million interferon-beta, 6 million 8 times. Indirect Coomb's test turned from negative to positive through IFN therapy and a complication of asymptomatic primary biliary cirrhosis was confirmed by histologic findings of the biopsied liver which was performed during IFN therapy and a presence of anti-mitochondrial antibody. After stopping IFN therapy and adding prednisolone anemia improved in getting negative indirect Coombs test but remaining positive direct Coombs test.

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation. Discover the latest research on AIHA here.

Related Papers

Annali italiani di medicina interna : organo ufficiale della Società italiana di medicina interna
F MocciaP Boccaccio
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Toru Shizuma
Digestive Diseases and Sciences
Pilar Sánchez-PobreJa Solís-Herruzo
© 2021 Meta ULC. All rights reserved