A case of bilateral keratitis caused by Providencia alcalifaciens: a rarely encountered ocular pathogen

International Ophthalmology
Won ChoiKyung Chul Yoon

Abstract

To report a case of keratitis caused by Providencia alcalifaciens. A 70-year-old man presented with pain, redness, and decreased vision in both of his eyes. On initial presentation, the visual acuity in both of his eyes was hand motion, and slit lamp examination showed diffuse infiltrates and total epithelial defects of the cornea, conjunctival hyperemia, and severe anterior chamber reactions with 2-mm-height hypopyon. The results of laboratory studies revealed elevated liver function tests, which indicated the presence of alcoholic liver disease. The culture result was positive for P. alcalifaciens and showed sensitivity to ceftazidime and amikacin but resistant to cefazolin, gentamicin, fluoroquinolone, and ampicillin. He was treated with topical application and intravenous injection of ceftazidime. His keratitis resolved gradually over 3 months as the treatment dose was tapered and the treatment was eventually discontinued. His final visual acuity was 20/200 in the right eye and 20/60 in the left eye because of the remaining central corneal opacity. We report a first case of keratitis due to P. alcalifaciens in a chronic heavy alcohol drinker. Ophthalmologists should consider this bacterium as a potential pathogen of corneal...Continue Reading

References

Dec 1, 1992·Infection and Immunity·M J AlbertJ Montanaro
Jul 8, 1989·BMJ : British Medical Journal·J Haynes, P M Hawkey
Sep 28, 2001·The Journal of Infectious Diseases·T MurataT Honda
Jun 29, 2002·Journal of Travel Medicine·Roman ChlibekJiri Beran
Aug 4, 2004·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Johannes FrankChristine Schütt
Mar 4, 2006·International Journal of Systematic and Evolutionary Microbiology·Vishal S SomvanshiErko Stackebrandt
Jun 27, 2006·Ophthalmology·Aaleya F KoreishiCarol L Karp
May 2, 2009·International Journal of Systematic and Evolutionary Microbiology·Punita Juneja, Brian P Lazzaro
Jul 19, 2013·The Journal of General and Applied Microbiology·Suwannee KhunthongpanAran H-Kittikun
Sep 10, 2013·Biochemistry. Biokhimii︠a︡·O G OvchinnikovaY A Knirel
Jul 1, 2015·The American Journal of Tropical Medicine and Hygiene·Mohammad Monir ShahYoshio Ichinose

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Citations

Dec 25, 2019·Current Eye Research·Pranita SahayJeewan S Titiyal
Aug 28, 2021·International Journal of Environmental Research and Public Health·Kousar Banu HoorzookNickey Janse van Rensburg

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