A Case of Brodie's Abscess With Tibial Erosion and Extravasation Into Surrounding Soft Tissue

Curēus
Josh LoweJoshua Oliver

Abstract

Atraumatic limb pain and limp is a common pediatric presentation in the emergency department in the United States. In a majority of cases, these presentations are benign. However, in cases where pediatric patients are repeatedly presenting for atraumatic limb pain, further investigation is required. We present such the case of a 14-year-old female with acute worsening of progressive atraumatic knee pain who was found to have a Brodie's abscess, a subacute pyogenic form of osteomyelitis. This is a particularly challenging diagnosis, as it often presents with no associated symptoms such as fever or weight loss. The consequences of missing this diagnosis include permanent disability and potential amputation, but excellent outcomes can be expected for those who undergo timely surgical debridement and irrigation. We discuss the etiology, common presentations, and treatment of this rare but potentially limb-threatening disease in the hope that clinicians will consider this diagnosis in cases of persistent or progressive atraumatic limb pain.

References

Mar 1, 1985·Pediatric Emergency Care·J I Singer
Mar 14, 2001·The Journal of Bone and Joint Surgery. British Volume·M J BlythG C Bennet
Aug 12, 2009·Clinical Radiology·A DatirA Saifuddin
Jan 1, 1832·Medico-chirurgical Transactions·B C Brodie
Apr 25, 2012·The Journal of Bone and Joint Surgery. British Volume·J DartnellM Katchburian
May 18, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Charles SchlurRaphaël Vialle
Sep 17, 2014·JBR-BTR : Organe De La Société Royale Belge De Radiologie (SRBR) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (KBVR)·M S SiddiquiS H Khan
Feb 14, 2019·Journal of Bone and Joint Infection·Niels van der NaaldDetlef van der Velde

❮ Previous
Next ❯

Citations

Aug 24, 2021·Curēus·Muhammad SalikShobit Verma

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
amputation

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The British Journal of General Practice : the Journal of the Royal College of General Practitioners
Neville Goodman
The American Journal of Orthopedics
W C Peh
Zahnãrztliche Welt, zahnãrztliche Rundschau, ZWR, vereinigt mit Zahnãrztliche Reform
K H Schmitz
Journal of the American Podiatry Association
R L BlakeJ P Colson
SADJ : Journal of the South African Dental Association = Tydskrif Van Die Suid-Afrikaanse Tandheelkundige Vereniging
M Otto
© 2021 Meta ULC. All rights reserved