A case of clear cell adenocarcinoma of the uterine cervix in pregnancy

Gynecologic Oncology
S InoueM Maeyama

Abstract

An extremely rare case of clear cell adenocarcinoma of the uterine cervix in pregnancy is reported. The primary lesion was first found at 34 weeks of pregnancy in a 34-year-old patient, and was cytologically suspected to be malignant. At 39 weeks of pregnancy, the patient underwent abdominal cesarean section concomitantly with removal of huge right ovarian tumor (3050 g) and delivered a normal male baby weighing 3590 g. Histological findings for cone biopsy at 22 days postpartum revealed invasive adenocarcinoma, and abdominal radical hysterectomy and pelvic lymphoadenectomy were performed at 36 days postpartum. Microscopically, the tumor tissue was composed of clear and hobnail-type cells. It showed a considerable amount of PAS-positive diastase-labile glycogen but was only weakly positive for immunoperoxidase staining of carcinoembryonic antigen.

References

Apr 1, 1976·British Journal of Obstetrics and Gynaecology·M C Anderson, A C Fraser
Jan 1, 1972·Cancer·W R Hart, H J Norris
Mar 1, 1982·The American Journal of Surgical Pathology·C CohenL R Budgeon

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Citations

May 12, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·K Van CalsterenF Amant
Jan 1, 2012·The American Journal of Case Reports·Sophie LuksW Dwayne Lawrence

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