A case of Cronkhite-Canada syndrome presenting with adenomatous and inflammatory colon polyps.

Nature Reviews. Gastroenterology & Hepatology
Seth SweetserLisa A Boardman

Abstract

A 72-year-old man was referred for evaluation of dysgeusia, diarrhea and anorexia. 3 months prior he began to experience taste changes, a decline in appetite and 3-7 loose, non-bloody stools per day. Nausea and lower abdominal cramping subsequently developed and he lost 22.68 kg in weight. His past medical history included atrial fibrillation treated with anticoagulation and digoxin. In the past, he had experienced markedly increased levels of triglycerides and was being treated for this condition with a lipid-lowering agent. There was no family history of colorectal neoplasia or IBD. He was a non-smoker and did not drink alcoholic beverages. Medical history, physical examination, laboratory evaluation (including 72 h stool collection), upper endoscopy, colonoscopy and histologic analysis of biopsy samples. Cronkhite-Canada syndrome. Prednisone (40 mg orally once daily, eventually tapered to 10 mg orally once daily), a histamine-2-receptor blocker and oral micronutrient supplementation (iron, vitamins A, E and D and a multivitamin). Removal of all visible polyps from the anal verge to 25 cm endoscopically by snare polypectomy or with hot biopsy forceps, followed by subtotal colectomy with end-to-side ileorectostomy.

References

Nov 1, 1989·The American Journal of Surgical Pathology·A P Burke, L H Sobin
Apr 1, 1986·Annals of Internal Medicine·D M FerneyR E Clouse
Apr 1, 1986·Journal of Clinical Gastroenterology·L B RappaportA Stavrides
Jan 1, 1985·The American Journal of Surgical Pathology·Y KatayamaM Konn
Mar 1, 1985·Journal of Clinical Pathology·D JenkinsB B Scott
Sep 1, 1984·The American Journal of Medicine·A F Jones, D B Paone
Oct 28, 1999·Gastrointestinal Endoscopy·T WatanabeT Chiba
Mar 6, 2002·Alimentary Pharmacology & Therapeutics·E M Ward, H C Wolfsen
Mar 5, 2003·Expert Opinion on Pharmacotherapy·Eric M Ward, Herbert C Wolfsen
Jun 24, 2003·The American Journal of Gastroenterology·Rajagopal ChadalavadaShahriar Sedghi
Jul 19, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·J NagataT Mine
Jun 16, 1955·The New England Journal of Medicine·L W CRONKHITE, W J CANADA
Feb 3, 2004·Digestion·Masakazu YashiroKosei Hirakawa
May 19, 2007·Digestion·Douglas L Riegert-JohnsonLisa A Boardman
Nov 28, 2007·Annual Review of Pathology·Thea D Tlsty, Lisa M Coussens

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Citations

Dec 27, 2013·Gastroenterology Research and Practice·Marcela KopáčováIlja Tachecí
Jun 28, 2016·Seminars in Ultrasound, CT, and MR·Nyree Griffin, Olwen Westerland
Jan 18, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N E SamalaviciusH Zažeckis
Nov 24, 2012·Journal of Digestive Diseases·Lin Yun XueQin Ouyang
Oct 2, 2012·Diagnostic and Interventional Imaging·C SellalD Régent
Dec 19, 2014·Clinical Journal of Gastroenterology·Seisuke OtaTadashi Matsumura
Jul 10, 2014·Journal of Clinical Pathology·Tomas Slavik, Elizabeth Anne Montgomery
Oct 18, 2019·ACG Case Reports Journal·Eric J MaoSean Fine
Jul 31, 2018·Case Reports in Medicine·S A TaylorD E Loomes
Oct 21, 2020·Clinical Journal of Gastroenterology·Ikuhiro KoboriMasaya Tamano
Nov 10, 2020·Gastroenterology Report·Ze-Yu WuBing Chang

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