A case of diffuse panbronchiolitis (DPB) in a patient positive for HTLV-1

Scandinavian Journal of Infectious Diseases
Osamu MatsunoTosihide Kumamoto

Abstract

Diffuse panbronchiolitis (DPB), an important cause of progressive obstructive lung disease in the Far East, represents a distinctive sinobronchial syndrome with typical radiologic and histologic features. Human T-cell lymphotrophic virus (HTLV-1) is a retrovirus that clinically and experimentally suppresses T-cell function and immune responses. The clinical and immunologic features of DPB in HTLV-1 carriers are unclear, because DPB and HTLV-1 endemic areas around the world are mostly non-overlapping. However, both diseases are endemic in Japan. We present a patient with DPB positive for HTLV-1 whose cellular and humoral immune responses were markedly impaired. Six y after diagnosis of DPB, the patient developed respiratory failure and died in spite of treatment with clarithromycin.

References

Jun 1, 1990·The American Review of Respiratory Disease·Y SugiyamaF Takaku
Nov 21, 1987·Lancet·M SugimotoS Kawasaki
Dec 15, 1988·International Journal of Cancer. Journal International Du Cancer·N TachibanaN Mueller
Jun 25, 1998·American Journal of Respiratory and Critical Care Medicine·S KudohM Ando
Oct 26, 1999·Journal of Acquired Immune Deficiency Syndromes : JAIDS·G P TaylorJ N Weber
Jun 19, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·E M CarvalhoF Neva

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Citations

May 27, 2011·Respiration; International Review of Thoracic Diseases·Rui-e FengQuan-cai Cui
May 6, 2010·Archives of Pathology & Laboratory Medicine·Timothy Craig Allen

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