PMID: 7083918Jul 1, 1982Paper

A case of eosinophilic pneumonia. Unusual immune complex vasculitis in the skin

Chest
N H ChanJ C Hogg

Abstract

This report concerns a 28-year-old woman with biopsy-proved eosinophilic pneumonia and cutaneous vasculitis. The skin biopsy specimen contained prominent granular deposits of IgM and C3 in dermal vessels, and elevated circulating immune complexes were detected. The association of cutaneous immune complex vasculitis with circulating immune complexes in chronic eosinophilic pneumonia is unusual and to our knowledge has not been previously reported. While the pathogenesis of chronic eosinophilic pneumonia is unknown, circulating immune complexes may represent a mechanism in the development of tissue eosinophilia.

References

Dec 1, 1975·The Journal of Experimental Medicine·R A ClarkA P Kaplan
Mar 1, 1976·Clinical Allergy·M Turner-WarwickM Lockwood
Aug 1, 1979·The Journal of Allergy and Clinical Immunology·J E ParrilloA S Fauci
Aug 1, 1978·Annals of Internal Medicine·J E ParrilloS M Wolff
Nov 1, 1971·The Journal of Allergy and Clinical Immunology·C E Laster, G J Gleich
Jun 1, 1968·Annals of Internal Medicine·W R Hardy, R E Anderson
Apr 10, 1969·The New England Journal of Medicine·C B CarringtonE A Gaensler

Citations

Oct 27, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·P-G SatorF Breier
Jun 18, 1998·Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna·M Suárez Tembra, S Pardo Barro

Related Concepts

Immune complex
Biopsy
Complement C3 precursor
IgM2
Lung
Tropical Eosinophilic Pneumonia
Skin
Vasculitis, Leukocytoclastic, Cutaneous

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