A case of flavor-induced lung disease

Southern Medical Journal
Preeti ModiRobert A Balk

Abstract

Bronchiolitis obliterans, a rare inflammatory disorder of the small airways, has been associated with various infections, aspiration, toxic fume inhalation, drugs, transplants, and collagen vascular disorders. In May 2000, this condition was described in eight workers in a microwave popcorn plant in Missouri. Subsequent studies reported its association with exposure to volatile organic compounds used in butter flavoring. Diacetyl was found to be the most predominant of these compounds. We report a case of this rare but serious disease in a 41-year-old flavor industry worker who was initially diagnosed with occupational asthma.

References

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Citations

Apr 17, 2008·Southern Medical Journal·Maureen R Horton
Nov 3, 2015·American Journal of Industrial Medicine·Rachel L BaileyKathleen Kreiss
Sep 28, 2017·Journal of Occupational and Environmental Medicine·Daniel E BanksMichael J Morris
Sep 23, 2019·Respirology : Official Journal of the Asian Pacific Society of Respirology·Miranda P WeenSandra J Hodge
Mar 25, 2009·Current Opinion in Allergy and Clinical Immunology

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