A case of freeze-dried gas gangrene antitoxin for the treatment of Clostridium perfringens sepsis

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
Juichiro YoshidaNorimasa Yoshida

Abstract

A 66-year-old man was admitted to our hospital with high fever. We diagnosed a gas-containing liver abscess and performed percutaneous abscess drainage. However, 15 hours after admission, he developed massive intravascular hemolysis and acidosis. Sepsis due to Clostridium perfringens was suspected and we treated the patient intensively with multidisciplinary approaches, including antibiotics, mechanical ventilation, and renal replacement therapy. Furthermore, we administered freeze-dried gas gangrene antitoxin. Despite intensive care, the patient died 43 hours after admission.

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