A case of general paresis showing marked treatment-associated improvement of cerebellar blood flow by quantitative imaging analysis

Annals of Nuclear Medicine
Masayuki MorikawaToshifumi Kishimoto

Abstract

We describe a patient with general paresis who developed progressive dementia and a cerebellar syndrome including wide-based gait, slurred speech, and intention tremor. Quantitative analysis by means of a Patlak plot of single-photon emission computed tomography (SPECT) with 99mTc-ethyl cysteinate dimer showed generally low blood flow in the cerebrum and the cerebellum. After antisyphilitic therapy, blood flow in the brain, especially in the cerebellum, improved noticeably, as did the cognitive disorder and the cerebellar syndrome.

References

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Nov 5, 1997·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R TakeuchiJ Konishi
Nov 20, 1998·Acta Psychiatrica Scandinavica·K FountoulakisC Ierodiakonou

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Citations

Jun 15, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Rezhan HusseinAnsaar T Rai
Mar 12, 2009·The Neurologist·Chen-Hsiang LeeJien-Wei Liu
Mar 2, 2021·Nuclear Medicine and Molecular Imaging·Eun Kyoung ChoiIn-Uk Song
Dec 4, 2021·Frontiers in Neurology·Jooyeon J ImYong-An Chung

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