A case of genital folliculosebaceous cystic hamartoma with an unique aggregated manifestation

The Journal of Dermatology
Manabu HamadaMasutaka Furue

Abstract

Folliculosebaceous cystic hamartoma (FCH) is a recently recognized cutaneous hamartoma composed of follicular, sebaceous and mesenchymal components, and usually occurring on the head and neck. We describe herein a case of FCH with an unique aggregated manifestation in a genital lesion. The patient was a 40-year-old woman with a genital lesion composed of a pedunculated nodule, a dome-shaped nodule and a subcutaneous nodule, measuring 5 cm in the greatest dimension. The largest, pedunculated nodule was histologically composed of an infundibulo-cystic structure with follicular, sebaceous and mesenchymal elements accompanied by cystic structures of various sizes lined by stratified squamous epithelium and follicular germinative cells suggesting follicular cysts. The dome-shaped nodule consisted of anastomosing strands of epithelial cells with follicular components. The subcutaneous nodule had two components, an infundibulo-cystic structure and a cyst lined by squamous epithelium. In our case, the unusual clinical feature of large and multiple nodules was due to the presence of several prominent hamartomatous cystic structures with FCH. This is the third case of giant FCH. The clinical presentation and location of giant FCH is unus...Continue Reading

References

Jun 1, 1991·The American Journal of Dermatopathology·T KimuraA B Ackerman
Jan 1, 1990·Dermatologica·M Nomura, S Hata
Apr 1, 1994·Journal of Cutaneous Pathology·O YamamotoJ Bhawan
Nov 1, 1993·The Journal of Dermatology·T YamamotoK Nishioka
Jun 1, 1993·The American Journal of Dermatopathology·P Donati, L Balus
Jan 1, 1996·Journal of the American Academy of Dermatology·S F Templeton
Feb 1, 1996·The American Journal of Dermatopathology·F AloiM Pippione
Jul 1, 1997·The Journal of Dermatology·M Toyoda, M Morohashi
Jun 27, 1998·Pathology·P K RamdialA Madaree
Nov 13, 1998·Dermatology : International Journal for Clinical and Investigative Dermatology·J L Bolognia, B J Longley
Mar 19, 1999·Journal of Cutaneous Pathology·R S SimónE Sánchez Yus
Oct 27, 2001·International Journal of Dermatology·M A El-DaroutyH M Mashaly
Feb 27, 2004·Journal of Cutaneous Pathology·David E SturtzDouglas R Fullen

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Citations

Jan 10, 2012·Annales de dermatologie et de vénéréologie·C Merklen-DjafriB Cribier
Aug 22, 2008·Journal of Cutaneous Pathology·Jose M Suarez-PeñarandaJerónimo Forteza-Vila
Sep 22, 2011·The Journal of Dermatology·Li-Qiang Zheng, Xiang-Chun Han
Dec 8, 2011·Annals of Dermatology·Seongmin NohMi Ryung Roh
May 30, 2009·Journal of Cutaneous Pathology·AbdullGaffar Badr, Ganapathy Raman Lakshmiah
Feb 1, 2009·Annals of Dermatology·Sik Haw, Mu-Hyoung Lee
Sep 17, 2009·The American Journal of Dermatopathology·Noriyuki MisagoYutaka Narisawa
Oct 5, 2010·The American Journal of Dermatopathology·Shin-ichi AnsaiSeiji Kawana
Jun 23, 2009·The American Journal of Dermatopathology·Ayman Al HabeebDanny Ghazarian
Jun 8, 2018·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Tomu OkadaIkuma Kato
Jan 29, 2011·The Journal of Dermatology·En Hyung KimYou Chan Kim

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