PMID: 22576393May 12, 2012Paper

A case of Good syndrome with pulmonary lesions similar to diffuse panbronchiolitis

Internal Medicine
Takaaki OgoshiHiroshi Mukae

Abstract

We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis.

Citations

Jan 5, 2016·Diagnostic and Interventional Imaging·G C ColinE Coche
Oct 17, 2016·Revue des maladies respiratoires·V ValentinB Wallaert
Jun 8, 2018·Current Opinion in Infectious Diseases·Ashrit MultaniJosé G Montoya
Jun 12, 2021·Frontiers in Immunology·Yiyun Shi, Chen Wang

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