PMID: 9436842Jan 22, 1998Paper

A case of hypopigmented mycosis fungoides in a young Caucasian boy

Pediatric Dermatology
A Di LandroT Cainelli

Abstract

Hypopigmented mycosis fungoides is a variant of mycosis fungoides characterized by the presence of hypopigmented patches as the sole manifestation of the disease. It has been described almost always in young black or dark-skinned patients. The only white patient described was a 64-year-old woman who not only had hypopigmented lesions, but also nodular lesions with lymphadenopathy. We describe hypopigmented lesions arising in a white boy 12 years of age, born in northern Italy, without any foreign ancestors. The microscopic alterations, with epidermotropism, the immunologic markers, the negativity of T-cell receptor gene rearrangement, and the good response to PUVA therapy correspond to the main findings in black patients with this disease. Long-term follow-up of these patients is important to obtain better knowledge of the natural history of the disorder. Hypopigmented mycosis fungoides must now be included in the differential diagnosis of hypopigmented macular lesions not only in black or dark-skinned patients but also in white patients.

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Citations

Dec 22, 1999·Journal of the American Academy of Dermatology·R AkaraphanthH W Lim
Nov 21, 2000·Pediatric Dermatology·I M NeuhausA M Hassanein
Jan 29, 2005·The American Journal of Dermatopathology·Betina WernerA Bernard Ackerman
Oct 4, 2006·Pediatric Dermatology·N OnsunN Büyükbabani
Jan 30, 2014·Anais Brasileiros De Dermatologia·Fabricio Cecanho Furlan, José Antonio Sanches
Feb 4, 2014·Journal of the American Academy of Dermatology·Oma N AgbaiHenry W Lim
Jul 31, 2007·Dermatologic Clinics·Medhat A El-MoftyMona R E Abdel-Halim
Mar 4, 1999·The Journal of Dermatology·M H Grunwald, B Amichai
Aug 16, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·I J RodneyR M Halder
Mar 20, 2004·Photodermatology, Photoimmunology & Photomedicine·S A Holme, A V Anstey
Sep 2, 2005·International Journal of Dermatology·Ayla GülekonOmür Ataoģlu
Jun 16, 2004·Journal of the European Academy of Dermatology and Venereology : JEADV·D V KazakovW Kempf
Oct 6, 2004·Pediatric Dermatology·Regina Fink-PuchesLorenzo Cerroni
Sep 26, 2000·Journal of Cutaneous Medicine and Surgery·M S QariM F Demierre

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