A case of large placental chorioangioma with non-immunological hydrops fetalis

Journal of Perinatal Medicine
Y MakinoT Kawarabayashi


A 34-year-old Japanese woman (gravida 2, para 2) with polyhydramnios and non-immunological hydrops fetalis was referred to our department at 32 weeks of gestation. On admission, the blood pressure was 120/60 mmHg and there was no pitting edema of the lower extremities. An ultrasound examination disclosed a large placental tumor 5.8 cm x 4.4 cm x 4.8 cm. Fetal lung compression was suspected because the lung-thorax transverse area ratio was 0.13. The preload index of the inferior vena cava was 0.74, suggesting fetal cardiac failure. After fetal pleural effusion was aspirated, lung compression developed. Cordocentesis was performed at 33 weeks of gestation, and the fetal karyotype was confirmed to be 46, XY from an umbilical blood cultivation. The patient underwent a cesarean section at 33 weeks of gestation due to severe uterine contraction after preterm PROM. The baby was a 3,840 g male with a distended abdomen. Apgar score at 1 minute was 1. A chest X-ray demonstrated respiratory distress syndrome. The baby was discharged on the 69th day after birth and he is now 2 years and 9 months old and healthy.


May 16, 2003·Journal of Perinatal Medicine·Michael GuschmannJoachim W Dudenhausen
Apr 17, 2004·Journal of Perinatal Medicine·Xander H T WehrensLouis L H Peeters


Jan 1, 1990·Fetal Diagnosis and Therapy·T Kanzaki, Y Chiba
Nov 1, 1995·American Journal of Obstetrics and Gynecology·S L Dorman, M S Cardwell
May 1, 1996·Journal of Computer Assisted Tomography·T MochizukiY Tsutsui

Related Concepts

Fetal Lung
Abdominal Cavity
Immune System Diseases
Postcesarean Section
Placenta Disorders
Immune Hydrops Fetalis
Pregnancy Complications, Neoplastic
Umbilical Blood

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