A case of malignant rhabdoid tumor arising from soft parts in the prepubic region.

Acta Pathologica Japonica
T TsujimuraS Mizutani

Abstract

An extrarenal malignant rhabdoid tumor arising from soft parts in the prepubic region of a 37-year-old man is described. This case appears to be unusual with regard to its location and age at onset. To our knowledge, the patient is the oldest recorded in whom such a lesion has arisen. Histologically, the tumor consisted of an admixture of polygonal and elongated cells with abundant eosinophilic cytoplasm frequently containing hyaline-like globules. Ultrastructurally, these cytoplasmic inclusions were compatible with intermediate filaments. Immunohistochemical staining disclosed keratin (non-squamous epithelial type) and epithelial membrane antigen positivity. These characteristic features were identical to malignant rhabdoid tumor of the kidney seen in infants and young children. This extrarenal malignant rhabdoid tumor showed an aggressive clinical course, although its exact histogenesis was unclear.

References

May 1, 1985·Cancer·H F FriersonD J Innes
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·S M JakateL Ingram
Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·T O EkforsM Kekomäki
Jun 15, 1985·Cancer·E J SmallB B Dahms
Apr 1, 1982·Human Pathology·G Zanetti, F Giangaspero
Jan 1, 1983·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·M MiettinenI Virtanen

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Citations

Jan 1, 1995·Journal of Neuro-oncology·L B RorkeJ Biegel
Feb 23, 2013·Sarcoma·Ryan HorazdovskyEdward Y Cheng
May 29, 2008·Pediatric Blood & Cancer·Franck BourdeautDaniel Orbach
Apr 1, 1993·Journal of the Royal Society of Health·A O Musaiger
Apr 29, 1998·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·A SuzukiM Shimada

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