PMID: 25743150Mar 7, 2015Paper

A case of metastatic cancer of unknown primary origin that progressed rapidly after complete remission via second-line chemotherapy

Gan to kagaku ryoho. Cancer & chemotherapy
Yuki AkazawaToshiki Funakoshi

Abstract

Leptomeningeal metastasis occurs in approximately 5% of patients with metastatic solid carcinomas, and it is often diagnosed in patients with breast cancer, lung cancer, malignant melanoma, and digestive cancer. Herein, we report a case of a metastatic cancer of unknown primary origin. The leptomeningeal metastasis progressed quite rapidly, and the patient died despite achieving complete remission via second-line chemotherapy.

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