PMID: 11925916Apr 3, 2002Paper

A case of mixed pulmonary infection with Mycobacterium tuberculosis and M. intracellulare due to familial prevalence

Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Yoshihiro KobashiT Matsushima

Abstract

A 76-year-old woman was admitted to our hospital because of an abnormal shadow on chest radiography and a suspected familial prevalence of pulmonary tuberculosis. Her son had previously been admitted to our hospital with pulmonary tuberculosis and tuberculous pleuritis. In the present case, a diagnosis of pulmonary tuberculosis and atypical pulmonary mycobacteriosis was made on the basis of detection of both Mycobacterium tuberculosis and M. intracellulare several times in a sputum culture of anti-fast bacilli. Restriction fragment length polymorphism (RFLP) analysis was then performed for both the woman and her son. The RFLP analysis revealed the same pattern in both mother and son, and confirmed that this was a case of mixed pulmonary infection passed from son to mother.

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