PMID: 16518069Mar 7, 2006Paper

A case of mucinous carcinoma of the breast that demonstrated a good pathological response to neoadjuvant chemotherapy despite a poor clinical response

Breast Cancer : the Journal of the Japanese Breast Cancer Society
Junpei YamaguchiMiyuki Takasugi

Abstract

A 30-year-old woman presented with a right breast tumor. Mucinous carcinoma was diagnosed by core needle biopsy (T2: 5 cm N1 M0). Despite receiving a neoadjuvant anthracycline and taxane regimen, the patient demonstrated no clinical response (NC). Based on the patient's strong preference, we performed breast-conserving surgery. On histological examination, we observed widespread mucus and a few viable malignant cells, a Grade 2 therapeutic response. Neither optimal management procedures nor guidelines for chemotherapy for primary mucinous carcinoma of the breast have been established. It is a reasonable assumption, however, that discordance between the clinical response and therapeutic response to neoadjuvant chemotherapy may occur in cases of mucinous carcinoma.

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Citations

Jun 25, 2010·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Takayoshi UematsuAkiko Ogiya
Mar 16, 2007·Neoplasia : an International Journal for Oncology Research·Klaus J SchmitzHideo A Baba
Feb 10, 2009·Clinical Breast Cancer·Foluso O Ademuyiwa, Kathy D Miller
Sep 5, 2008·Sleep Medicine Clinics·Wayne A Bardwell, Sonia Ancoli-Israel
Aug 28, 2007·The Breast : Official Journal of the European Society of Mastology·Angelo Di LeoLaura Biganzoli
Dec 29, 2006·Contrast Media & Molecular Imaging·Tristan BarrettHisataka Kobayashi
Nov 1, 2012·The Breast Journal·Tomoe NakagawaFujio Kasumi
Sep 22, 2012·Cytopathology : Official Journal of the British Society for Clinical Cytology·J CyrtaP Vielh
Apr 3, 2007·Analytical Biochemistry·Carmen CañadasMiguel de la Hoya
Jun 2, 2007·NMR in Biomedicine·Torill E SjøbakkIngrid S Gribbestad
Dec 23, 2006·Expert Review of Vaccines·Jeong-Im Sin
Jul 4, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hope S Rugo, Sara Keck

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