A case of nasal septal abscess caused by medication related osteonecrosis in breast cancer patient

Auris, Nasus, Larynx
Mayuka MaedaAkihiro Shiotani

Abstract

Antiresorptive drugs have been widely used to treat patients with hypercalcemia caused by malignancy, bone metastasis, multiple myeloma, and osteoporosis. However, it is well known that antiresorptive drugs can cause osteonecrosis of the jaw (ONJ). Herein, we report a rare case of nasal septal abscess caused by medication related osteonecrosis of the jaw (MRONJ) in a breast cancer patient. A 69-year-old woman was referred to our clinic for evaluation of nasal obstruction. Physical examination revealed a cherry-like swelling of the nasal mucosa emanating from the septum that obstructed both nasal cavities and a fistulous tract showing pus discharge after extraction of the bilateral maxillary central incisors (MCI) and the right maxillary lateral incisor (MLI). Computed tomography and panoramic radiography revealed extensive osteonecrosis of the maxilla and swelling of the nasal mucosa. The clinical diagnosis was nasal septal abscess caused by osteonecrosis of the maxilla. Surgical procedure was undertaken for this case. An indwelling drain was placed in the oral cavity, and sequestrectomy was performed with incision and drainage of the anterior portion of left nasal septum. The patient was doing well at the 7-month follow-up. Th...Continue Reading

References

Apr 1, 1987·Clinical Otolaryngology and Allied Sciences·H Kryger, H Dommerby
Sep 20, 2002·The Journal of Laryngology and Otology·Kenny Peter Pang, Dharambir S Sethi
May 4, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Salvatore L RuggieroStephen L Engroff
Mar 10, 2005·The Annals of Pharmacotherapy·Angelo A Licata
Nov 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Aristotle BamiasMeletios A Dimopoulos
May 17, 2006·Annals of Internal Medicine·Sook-Bin WooJohn R Kalmar
Aug 19, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Paolo VescoviMaddalena Manfredi
Dec 1, 2006·The New England Journal of Medicine·John P Bilezikian
Sep 23, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Salvatore L RuggieroFelice O'Ryan

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Citations

Feb 9, 2017·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Min HeYi-Ping You
Apr 30, 2021·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Sang Min Lee, Dae Ho Leem

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