A case of neck ectopic meningioma

Neuropathology : Official Journal of the Japanese Society of Neuropathology
Mohammad Hossein SaneiAzar Naimi

Abstract

Primary extra cranial and extra spinal meningioma is rare and is usually limited to the head and neck region or to the paravertebral soft tissues. Histologic diagnosis (in particular for fresh specimens) is often difficult. A 16-year-old girl with a cervical mass is presented. It was a relatively large mass with an approximate diameter of 5 cm. It was diagnosed in fine needle aspiration as a pleomorphic adenoma. Intra-operative diagnosis was paraganglioma and frozen section suggested an infiltrative tumor. Histologically, the lesion showed uniform spindle cell proliferation separated by hyalinized collagen bundles. The cells were often arranged in sweeping fascicles and concentrically wrapped in tight whorls. Immunohistochemically, tumor cells were positive for epithelial membrane antigen and vimentin, while showing no reaction for cytokeratin, chromogranin, neuron-specific enolase and thyroglobulin. A diagnosis of ectopic meningioma was established based on microscopic appearance and immunohistochemical profile of the tumor. Despite its rarity, ectopic meningioma should be considered in differential diagnosis of any mass lesion in head and neck regions, containing spindle cells.

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Citations

Oct 30, 2009·Southern Medical Journal·Fang Chen, Shucheng Zhang
Jun 11, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Mohammad Hossein SaneiHamid Reza Jafari
Jan 24, 2012·World Journal of Surgical Oncology·Akira MogiHiroyuki Kuwano
Jan 22, 2011·Cytopathology : Official Journal of the British Society for Clinical Cytology·M F QutubW E Khalbuss
Sep 9, 2010·Cancer·Austin MattoxCory Adamson
Apr 16, 2016·Diagnostic Cytopathology·Aqiba BokhariPatricia G Tiscornia-Wasserman
Oct 30, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Chunyue MaXingzhou Qu
Feb 16, 2021·Neurosurgery·Angus TolandSonika M Dahiya
May 28, 2021·BMJ Case Reports·Mahan SalehiJakub Kadlec

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