A case of non-hodgkin's lymphoma of the ovary: usefulness of 18F-FDG PET for staging and assessment of the therapeutic response

Annals of Nuclear Medicine
Daisuke KomotoMotoomi Ohkawa

Abstract

Primary ovarian lymphoma as the initial manifestation is rare. A 27-year-old woman presented to our hospital with the symptoms of lower abdominal fullness and pollakisuria. CT scan and MRI revealed bilateral ovarian tumors, which showed heterogeneous masses. 18F-FDG PET revealed strong uptake by the abdominal masses, and the maximum standardized uptake value (SUVmax) was 12.5. Abnormal uptake was not shown by other regions. An exploratory laparotomy was performed. Histological findings revealed diffuse large B-cell lymphoma. The clinical stage was IV according to the Ann Arbor system. International prognostic index (IPI) was 3 (high-intermediate risk). Chemotherapy was administered consisting of three courses of an R-CHOP regimen, and 18F-FDG PET and CT scan revealed no signs of involvement 3 months after initiation of the chemotherapy. 18F-FDG PET was a useful method for staging and assessment of the therapeutic response in primary ovarian lymphoma.

References

Aug 1, 1991·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·H RothK Schäfer
Aug 1, 1988·American Journal of Clinical Pathology·M D LindenW R Hart
Jun 23, 2000·Journal of Computer Assisted Tomography·F FerrozziG Zuccoli
Jul 11, 2001·Advances in Anatomic Pathology·R VangM Deavers
Aug 28, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K SpaepenG Verhoef

❮ Previous
Next ❯

Citations

Sep 1, 2010·Nuclear Medicine and Molecular Imaging·Da-Mi KimHyun Jin Son
Sep 1, 2011·Nuclear Medicine and Molecular Imaging·Rajan RakhejaMarc Hickeson
Dec 25, 2008·Expert Review of Anticancer Therapy·Sandip BasuAbass Alavi
Jan 12, 2011·Clinical Nuclear Medicine·Nalan CanMustafa Unlü
Feb 13, 2020·Clinical Nuclear Medicine·Jianhua ZhangLin Nong
Jan 22, 2015·Clinical Nuclear Medicine·Xia BaiHongming Zhuang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.