A case of orthologous sequences of hemocyanin subunits for an evolutionary study of horseshoe crabs: amino acid sequence comparison of immunologically identical subunits of Carcinoscorpius rotundicauda and Tachypleus tridentatus

Zoological Science
H Sugita, F Shishikura

Abstract

About 83% of the amino acid sequence of hemocyanin subunit HR6 from the Southeast Asian horseshoe crab, Carcinoscorpius rotundicauda, has been determined. There is a difference of about 43% between HR6 and complete sequences of chelicerate hemocyanin subunits from the American horseshoe crab, Limulus polyphemus, and a tarantula, Eurypelma californicum. However, the immunologically identical subunits HR6 and HT6 from Tachypleus tridentatus (Japanese horseshoe crab) show 2.7% sequence difference. Based on the amino acid sequences of HR6 and HT6, the divergence between C. rotundicauda and T. tridentatus occurred about 9.6 million years ago. In the case of horseshoe crab hemocyanin subunits, it seems that the orthologous homologues in many homologous subunits between species are immunologically detectable.

References

Mar 1, 1979·Archives of Biochemistry and Biophysics·J LamyJ Weill
Jul 1, 1979·Hoppe-Seyler's Zeitschrift für physiologische Chemie·J LamyB Linzen
Jul 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·W Voll, R Voit
Jun 1, 1987·Biological Chemistry Hoppe-Seyler·R DrexelF Lottspeich
Aug 9, 1985·Science·B LinzenT Takagi
Jan 1, 1983·Progress in Biophysics and Molecular Biology·H D EllertonH A Robinson
Oct 1, 1983·Hoppe-Seyler's Zeitschrift für physiologische Chemie·H J SchneiderA Henschen
Feb 1, 1982·Quarterly Reviews of Biophysics·K E van Holde, K I Miller
Dec 28, 1964·Annals of the New York Academy of Sciences·B J DAVIS

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Citations

Feb 5, 2000·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·P Dolashka-AngelovaW Voelter
Dec 31, 2002·Archives of Biochemistry and Biophysics·Dorothy D PlessEdgar P Heimer de la Cotera

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Methods Mentioned

BETA
electrophoresis
ion-exchange chromatography
gel filtration

Software Mentioned

Neighbor
Protdist
Phylip

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