A case of polyarteritis nodosa limited to the right calf muscles, fascia, and skin: a case report

Journal of Medical Case Reports
Saad AhmedDavid Kane

Abstract

Limited polyarteritis nodosa is a rare benign disease that usually responds well to systemic corticosteroid treatment. We report a case limited to calf muscles, fascia, and skin treated with local corticosteroid therapy directed to the affected areas by ultrasound guidance. A 36-year-old Caucasian woman presented with a 10-month history of progressive right calf pain and swelling, which were unresponsive to treatment with non-steroidal anti-inflammatory drugs and physiotherapy. An examination revealed a swollen tender right calf with indurated overlying skin. Laboratory investigations showed an erythrocyte sedimentation rate of 24 mm/hour and a C-reactive protein of 15 mg/dl. Full blood count, renal profile, and creatinine kinase level were normal. A full autoantibody screen and hepatitis B and C serology results were negative. A chest X-ray was unremarkable. Magnetic resonance imaging of the right leg revealed increased signal intensity in T2-weighted images and this was suggestive of extensive inflammatory changes of the gastrocnemius muscle and, to a lesser extent, the soleus muscle. There were marked inflammatory changes throughout the gastrocnemius muscle and the subcutaneous tissue circumferentially around the right lower...Continue Reading

References

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Citations

Jan 31, 2017·Rinshō shinkeigaku = Clinical neurology·Masayoshi YamamotoToshiaki Hamano
May 17, 2019·Case Reports in Rheumatology·H M SenarathnaT P Weerarathna
Mar 6, 2021·BMJ Case Reports·Ariana González-MeléndezLuis M Vilá

Methods Mentioned

BETA
X-ray
biopsy

Related Concepts

Adrenal Cortex Hormones
Azathioprine
Biopsy
C-reactive protein
Complete Blood Count
Erythrocytes
Fascia
Hepatitis B
Immunoglobulin G
Chronic Inflammation

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