A case of pregnancy associated hypereosinophilia with hyperpermeability symptoms

Gynecologic and Obstetric Investigation
Maki OgasaKazuyuki Ueda

Abstract

Hypereosinophilia commonly reflects an allergic, infectious, or neoplastic disease, and is a rare complication during pregnancy. A 27-year-old pregnant woman was referred to our hospital due to dyspnea at 10 weeks' gestation. Ultrasound examination showed the presence of pericardial effusion, pleural effusion, and ascites. Fluid transfusion, diuretic administration, and oxygen supplementation gradually improved the symptoms. Thereafter, the blood eosinophil count increased acutely and the fetus died. Following cessation of pregnancy the blood eosinophil count gradually decreased. Laboratory examinations did not assist the diagnosis of eosinophilia. This is the first case of hypereosinophilia associated with the life-threatening hyperpermeability symptoms, i.e., pericardial effusion, pleural effusion, and ascites, during early pregnancy.

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May 1, 1997·Acta Obstetricia Et Gynecologica Scandinavica·A E AlbrechtP W Husslein
Apr 16, 2003·British Journal of Haematology·Finella Brito-Babapulle
Jun 11, 2003·Archives of Internal Medicine·Joanna Thompson CoonEdzard Ernst

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Citations

May 25, 2011·World Journal of Gastrointestinal Pathophysiology·Iryna S HepburnRobert R Schade
Dec 21, 2012·Gastroenterology·Ravi B ParikhLawrence R Zukerberg
Feb 27, 2009·British Journal of Haematology·Gerald J Gleich, Kristin M Leiferman
Jul 4, 2008·Leukemia Research·Patricia AultSrdan Verstovsek
Oct 16, 2012·Expert Review of Gastroenterology & Hepatology·Alfredo J Lucendo, Angel Arias

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