Oct 1, 1989

A case of refractory testicular cancer showing complete response to high-dose chemotherapy with autologous bone marrow transplantation

Gan to kagaku ryoho. Cancer & chemotherapy
H IshiiS Asano


A patient with stage III testicular cancer was treated by 3 courses of BEP therapy and a partial response was obtained. Afterwards he underwent resection of pulmonary residual tumors and was treated by 2 courses of PE therapy immediately after operation. However, a new pulmonary tumor appeared after the first course of PE therapy was completed. He was treated by high-dose chemotherapy (etoposide 1200 mg/m2, cyclophosphamide 120 mg/kg, CDDP 60 mg/m2) with autologous bone marrow transplantation. Three weeks after high-dose chemotherapy his metastatic pulmonary tumor showed cavity formation which disappeared after 3 months. Fifteen months after the high-dose chemotherapy, no evidence of disease has been seen even without maintenance therapy.

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Mentioned in this Paper

Antineoplastic Chemotherapy Protocols
Mature Teratoma
Combined Modality Therapy
Testicular Neoplasms
Remission Induction
Transplantation, Autologous
Drug Resistance
Bone Marrow Cell Transplantation

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