A case of Sézary syndrome with non-rosetting cells and unusual cytogenetic findings

Acta Haematologica
S H AdvaniG V Talvalkar

Abstract

A rare case of Sézary syndrome with typical, clinical and haematological picture is described. The absence of any lymphoid surface markers on Sézary cells and the consistent presence of distinct clone 45 XY-F cytogenetic abnormality are very unusual features observed in the present case. In spite of these peculiar findings, response to chlorambucil and prednisolone was excellent.

Citations

Mar 15, 1985·Cancer Genetics and Cytogenetics·M SchmidtE Neumann
Jul 1, 1987·Cancer Genetics and Cytogenetics·R Berger, A Bernheim
Nov 1, 1983·Scandinavian Journal of Immunology·C Farnarier-SeidelR Depieds

Related Concepts

Surface Antigens
B-Lymphocytes
Plasma Membrane
Autosome Abnormalities
Chromosomes, Human,19-20
Chromosomes, Human,21-22
Lymphoid Cells
Immunocytoadherence
Sezary Syndrome
T-Lymphocyte

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