PMID: 9788270Oct 27, 1998Paper

A case of small cell carcinoma arising in a mature cystic teratoma of the ovary

Pathology International
S C LimC H Suh

Abstract

Malignant transformation of ovarian mature cystic teratomas is reported to occur in about 1% of cases. The most common malignant evolution is that of squamous cell carcinoma and one of the least common is that of small cell carcinoma. We report a case of distant metastasis from a small cell carcinoma arising in a mature cystic teratoma. A 28-year-old nulliparous female presented with signs of supraclavicular lymph node metastasis. This is the first known case report of lymph node metastasis as an initial sign of cancer developing in a pre-existing mature cystic teratoma. Histologically, the tumor cells had microscopic features similar to those of pulmonary small cell carcinoma. This report gives a literature review, and the histological, immunohistochemical, flow cytometric and ultrastructural features are described.

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Citations

Jul 31, 2013·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Akiko KurasakiKaneyuki Kubushiro
Jul 1, 2010·Indian Journal of Cancer·M MadanS Sharma
Oct 23, 2013·Seminars in Diagnostic Pathology·Marjan Rouzbahman, Blaise Clarke
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Jun 11, 2004·Pathology International·Yukio TakeshimaKouki Inai
Sep 27, 2018·The American Journal of Surgical Pathology·Chia-Sui KaoThomas M Ulbright
Mar 2, 2019·Diagnostic Cytopathology·Parikshaa GuptaChandan Krushna Das
Oct 27, 2004·Advances in Anatomic Pathology·W Glenn McCluggage
Aug 11, 2020·International Journal of Surgical Pathology·Parikshaa GuptaRadhika Srinivasan
Oct 5, 2019·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Robert HarknessW Glenn McCluggage
Jul 25, 2017·Current Oncology Reports·Brooke E HowittW Glenn McCluggage
May 21, 2015·International Journal of Surgical Pathology·Alejandro RubioFrancisco F Nogales
Sep 1, 2018·Journal of Ovarian Research·Kazuya MaedaMasahide Ohmichi

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