A case of steroid responsive pulmonary hyalinising granuloma: complicated by deep venous thrombosis

The European Respiratory Journal
K M A O'ReillyP J Sime

Abstract

A case of pulmonary hyalinising granuloma (PHG) complicated by deep venous thrombosis (DVT) is presented. The DVT was associated with the presence of a lupus anticoagulant. In the past PHG has been linked to various auto-antibodies, but to the best of the authors' knowledge, this is the first case reporting PHG in association with a lupus anticoagulant and clinically significant venous thrombosis. Historically, PHG has been regarded as poorly corticosteroid responsive. However, the patient in this case study responded dramatically to prednisone. This case study suggests that in selected patients with pulmonary hyalinising granuloma experiencing disabling symptoms and worsening pulmonary function, a trial of corticosteroids may be warranted.

Citations

Apr 1, 2009·Journal of Bronchology & Interventional Pulmonology·Imran KhalidPaul Kvale
Apr 25, 2008·Pediatric Hematology and Oncology·Funda CorapçiogluGorkem Aksu
Apr 20, 2014·Journal of Clinical Imaging Science·Christopher ColemanBarbara McComb
Nov 19, 2010·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Guilherme D'Andréa Saba ArrudaFelipe Shigueo Passos Tozaki

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