PMID: 15218965Jun 29, 2004Paper

A case of T-cell acute lymphoblastic leukemia after treatment of acute promyelocytic leukemia

International Journal of Hematology
P C BeeK Y Goh

Abstract

We diagnosed T-cell acute lymphoblastic leukemia (T-ALL) with multiple cytogenetic abnormalities in a 17-year-old girl a year after she had received a diagnosis of acute promyelocytic leukemia (APML). After the diagnosis of APML in June 2001, the patient was treated with idarubicin and all-trans-retinoic acid. In September 1999, her younger sister also received a diagnosis of APML and to date has remained well. T-ALL after remission of APML is very rare, and only 1 such case has been reported. Possible causes include therapy-related reasons, genetic susceptibility to leukemia, and environmental exposure.

References

Aug 12, 1999·British Journal of Haematology·L DawsonJ C Kluin-Nelemans
Mar 18, 2000·Leukemia & Lymphoma·V PratesJ Milone
Apr 12, 2003·Leukemia & Lymphoma·J KuruvillaJ H Lipton

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Citations

Dec 21, 2007·Leukemia Research·Patrice ChevallierRichard Garand
Nov 13, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·A L Dunn
May 26, 2006·Antimicrobial Agents and Chemotherapy·Manuel Cuenca-EstrellaJuan L Rodriguez-Tudela
Jul 26, 2019·Journal of Pediatric Hematology/oncology·Rachel A MarianiShunyou Gong

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