A case of veno-occlusive disease following liver transplantation

Experimental and Therapeutic Medicine
Hong ChenZhongyang Shen

Abstract

The present case report describes the diagnosis and treatment of a patient with veno-occlusive disease (VOD) following liver transplantation. Combining the clinical data and relevant literature, the study aimed to consider the causes of VOD following liver transplantation, and the pathogenesis, clinical diagnosis and auxiliary examination features of VOD. A 42-year-old man who had a long history of taking traditional Chinese medicine (essential components unknown) underwent an orthotropic liver transplantation on January 14, 2011, due to small venous occlusion disease of the liver. The patient was treated with tacrolimus as an antirejection therapy following the surgery, and gradually developed right upper quadrant pain and fatigue. The examination results were consistent with the diagnostic standards for VOD. Following treatment with methylprednisolone, the patient was treated with alprostadil and Danhong injections. Forty days later, the patient's total bilirubin (TBIL) level was observed to have decreased significantly, the liver function had returned to normal and the ascites had decreased, but had not completely disappeared. The patient then underwent a transjugular intrahepatic portosystemic shunt (TIPS) procedure, follow...Continue Reading

References

Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G B McDonaldE D Thomas
Aug 1, 2007·World Journal of Gastroenterology : WJG·M SenzoloA-K Burroughs
Jun 16, 1945·British Medical Journal·A L McFarlane, W J Branday
Aug 26, 2011·Journal of Pediatric Gastroenterology and Nutrition·Laura J WozniakSteven S Wu
Jun 5, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Nida Fatma TascilarBanu Ozen Barut
Oct 10, 2013·British Journal of Haematology·Fiona L DignanUNKNOWN British Society for Blood and Marrow Transplantation

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