A case of Wong-type dermatomyositis treated with rituximab and IVIG.

The Australasian Journal of Dermatology
Yahya ArgobiSara R Schoenfeld

Abstract

A 37-year-old woman presented to our rheumatology-dermatology clinic with a rash, muscle weakness and fatigue. She has had prior diagnoses of cutaneous lupus and lichen planus based on skin biopsies. She did not respond to topical steroids, hydroxychloroquine and dapsone. Clinically, she had sharply demarcated photo-distributed erythema over the upper back, chest and upper arms, along with hyperkeratotic follicular papules on bilateral upper arms, shoulders, posterior neck, behind the ears, chest including breasts, abdomen and right buttock. Investigations revealed a high titre ANA, elevated creatinine kinase, aldolase and positive anti-MJ/nuclear matrix protein 2 (NXP-2). A skin biopsy showed findings of connective tissue disease. The diagnosis of Wong-type dermatomyositis was made. She responded to therapy with mycophenolate mofetil, rituximab and IVIG.

References

Jul 1, 1969·The British Journal of Dermatology·K O Wong
Dec 1, 1956·A.M.A. Archives of Dermatology·L A BRUNSTINGH O PERRY
Oct 2, 2015·Clinical Reviews in Allergy & Immunology·Minoru SatohEdward K L Chan
May 11, 2016·Journal of Cutaneous Pathology·Diya F MutasimKerith E Spicknall
Feb 21, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Matthew T KoroscilJoshua N Scott

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Related Papers

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia
Dario DidonaBiagio Didona
The Journal of Dermatology
Masato Ishikawa, Toshiyuki Yamamoto
Arthritis & Rheumatology
Christina E BaxVictoria P Werth
Dermatology Practical & Conceptual
Mario DiplomaticoRita Sottile
Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
Matthew T KoroscilJoshua N Scott
© 2021 Meta ULC. All rights reserved