A case report of anaphylaxis to Typhoid Vaccine Live Oral Ty21a (Vivotif)

Journal of Travel Medicine
Nathan L HaasCharmaine Gregory

Abstract

Typhoid Vaccine Live Oral Ty21a (Vivotif) is typically well tolerated, and adverse events are infrequent and mild. To the best of the authors' knowledge, only one prior anaphylactic reaction has previously been reported. We present a case of anaphylaxis related to Vivotif, in which a 66-year-old male with no medical comorbidities developed anaphylaxis following the third of a four-dose course (in the absence of concomitant vaccination administration), which consisted of tongue swelling, difficulty breathing, abdominal discomfort and rash. He was managed with epinephrine, corticosteroids and antihistamines.

Citations

Feb 8, 2021·Journal of Travel Medicine·Abi ManeshPriscilla Rupali
Aug 20, 2021·Advanced Drug Delivery Reviews·Yuandong ZhangXun Sun

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