A case report of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein tumor embolism.

World Journal of Gastroenterology : WJG
Yusuke TanoueAya Yokota

Abstract

We report a case of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein (IMV) tumor embolism. A 79-year-old woman was admitted to our hospital with narrowing of the stools. We performed colonoscopy, computed tomography and positron emission tomography, which disclosed sigmoid colon cancer with IMV tumor embolism. She underwent sigmoidectomy and lymph node dissection. The tumor was diagnosed as endocrine cell carcinoma (type 4, pSS, med, INFalpha, v3, n1, stage IIIb). Immunohistochemically, chromographin A, synaptophysin, cytokeratin 20 and mucicarmine showed partial staining, and CD56 was totally reactive. Three months after operation multiple liver metastases appeared. She was treated with chemotherapy of cisplatin (CDDP) + irinotecan (CPT11). This case highlights the aggressiveness of endocrine cell carcinoma with tumor embolism, and it is essential to establish an accurate diagnosis and effective treatment.

References

Mar 1, 1991·American Journal of Clinical Pathology·A B BurkeL H Sobin
Jan 1, 1990·Cancer·B H FederspielK M Shekitka
Aug 1, 1995·Pathology International·M VilorF Ueno
Jan 11, 2002·The New England Journal of Medicine·Kazumasa NodaUNKNOWN Japan Clinical Oncology Group
Jan 13, 2004·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Ken NishikuraYoichi Ajioka
Mar 27, 2004·Diseases of the Colon and Rectum·P E BernickW D Wong

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Citations

Oct 4, 2016·Asian Journal of Surgery·Kensuke OtaniToshiaki Watanabe
Aug 17, 2019·World Journal of Clinical Cases·Tomoaki YoshidaShuji Terai

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