A cellular perspective of adipogenesis transcriptional regulation

Journal of Cellular Physiology
Walid Kuri-HarcuchVeronica Fernandez-Sanchez

Abstract

Adipose cells store lipids in the cytoplasm and signal systemically through secretion of adipokines and other molecules that regulate body energy metabolism. Differentiation of fat cells and its regulation has been the focus of extensive research since the early 1970s. In this review, we had attempted to examine the research bearing on the control of adipose cell differentiation, some of it dating back to the early days when Howard Green and his group described the preadipocyte cell lines 3T3-L1 and 3T3-F442A during 1974-1975. We also concentrated our attention on research published during the last few years, emphasizing data described on transcription factors that regulate adipose differentiation, outside of those that were reported earlier as part of the canonical adipogenic transcriptional cascade, which has been the subject of ample reviews by several groups of researchers. We focused on the studies carried out with the two preadipocyte cell culture models, the 3T3-L1 and 3T3-F442A cells that have provided essential data on adipose biology.

References

Dec 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·W Kuri-Harcuch, H Green
Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·J Pairault, H Green
Jan 1, 1985·Differentiation; Research in Biological Diversity·H GreenT Nixon
Sep 1, 1985·Journal of Cellular Physiology·P DjianH Green
Jan 1, 1984·Differentiation; Research in Biological Diversity·W Kuri-HarcuchM Marsch-Moreno
Jun 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·B T Nixon, H Green
Jul 1, 1982·Cell·M MorikawaH Green
Aug 25, 1995·Science·N D WangG J Darlington
May 15, 1994·Genes & Development·P TontonozB M Spiegelman
Apr 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·S MandrupM D Lane
May 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·J B KimB M Spiegelman
Mar 30, 1999·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·T TanakaS Akira
Aug 11, 2000·Science·S E RossO A MacDougald
Oct 14, 2000·Annual Review of Cell and Developmental Biology·E D Rosen, B M Spiegelman
May 8, 2002·Nature Reviews. Molecular Cell Biology·M Angela Nieto
Jan 10, 2003·The Journal of Biological Chemistry·Guillaume CharrièreLouis Casteilla
Aug 2, 2003·Journal of Cell Science·Leeni KoivistoHannu Larjava
Sep 1, 1963·The Journal of Cell Biology·L NAPOLITANO
Jan 25, 2005·The Journal of Biological Chemistry·Toshiyuki MoriMasato Kasuga
Feb 16, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S R Farmer
Apr 26, 2005·The Journal of Biological Chemistry·Jennifer A Kennell, Ormond A MacDougald
Aug 2, 2005·Cell Metabolism·Zhu ChenJeffrey M Friedman
Oct 3, 2006·Cell Metabolism·Stephen R Farmer
Feb 3, 2007·The Journal of Clinical Investigation·Olivier Le BacquerNahum Sonenberg

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Citations

Feb 7, 2020·The Biochemical Journal·Elizabeth A Rondini, James G Granneman
Jul 29, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Xiao-Fei ManHou-De Zhou
Oct 27, 2018·Pharmaceuticals·Stephanie RockfieldMeera Nanjundan
Jun 13, 2020·International Journal of Molecular Sciences·Carina da SilvaMichael S Pepper
Oct 20, 2020·Frontiers in Endocrinology·Ayelén Ivana Pesce VigliettiMaría Victoria Delpino
Dec 1, 2020·American Journal of Physiology. Endocrinology and Metabolism·Martine AuclairBénédicte Antoine
Jan 8, 2021·Toxicology and Applied Pharmacology·Tianchang GaoYanyan Chen
Sep 7, 2020·Differentiation; Research in Biological Diversity·Muhammad Sufyan VohraEng Hwa Wong
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alice RaineriMarta Menegazzi

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