PMID: 22353649Feb 23, 2012Paper

A challenge to appropriate antibiotic use in children with respiratory infections: a 5-year single-institution experience

Fukushima Journal of Medical Science
Ayumi MatsumotoMitsuaki Hosoya

Abstract

We have studied the rate of emergence of antibiotic-resistant Streptococcus pneumoniae (S. pneumoniae) and Haemophilus influenzae (H. influenzae) and the subsequent antibiotic use in host patients of those isolates at the Department of Pediatrics, Soma General Hospital, Fukushima. Moreover, we carried out several studies investigating the risks and benefits of antibiotic-free treatment for children with respiratory infections. In this report, we summarize our research and suggest better treatment options for pediatric patients with respiratory infections. We investigated the necessity of antibiotic use in the treatment of pediatric inpatients with respiratory syncytial virus (RSV) infection, and tested our hypothesis that antibiotic-free treatment for common cold will reduce the number of resistant S. pneumoniae strains in the pediatric nasopharynx. Therefore, we restricted prescribing antibiotics for pediatric patients with respiratory infections. The rates of resistant S. pneumoniae and H. influenzae and the medication history of the host patients before and after the intervention were compared. We found that most of the RSV-infected patients recovered without antibiotic treatment, and that the antibiotic-free treatment inhib...Continue Reading

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Citations

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Related Concepts

Antibiotics
Catarrh
Antibiotic Resistance, Microbial
Haemophilus Infections
Haemophilus influenzae
Pneumococcal Infections
Upper Respiratory Infections
Respiratory Syncytial Virus Infections
Inappropriate Prescribing
Klebsiella pneumoniae

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