A Chemical-Biological-Radio-Nuclear (CBRN) Filter can be Added to the Air-Outflow Port of a Ventilator to Protect a Home Ventilated Patient From Inhalation of Toxic Industrial Compounds

Disaster Medicine and Public Health Preparedness
Eliezer Be'eriArik Eisenkraft

Abstract

Chemical-biological-radio-nuclear (CBRN) gas masks are the standard means for protecting the general population from inhalation of toxic industrial compounds (TICs), for example after industrial accidents or terrorist attacks. However, such gas masks would not protect patients on home mechanical ventilation, as ventilator airflow would bypass the CBRN filter. We therefore evaluated in vivo the safety of adding a standard-issue CBRN filter to the air-outflow port of a home ventilator, as a method for providing TIC protection to such patients. Eight adult patients were included in the study. All had been on stable, chronic ventilation via a tracheostomy for at least 3 months before the study. Each patient was ventilated for a period of 1 hour with a standard-issue CBRN filter canister attached to the air-outflow port of their ventilator. Physiological and airflow measurements were made before, during, and after using the filter, and the patients reported their subjective sensation of ventilation continuously during the trial. For all patients, and throughout the entire study, no deterioration in any of the measured physiological parameters and no changes in measured airflow parameters were detected. All patients felt no subjectiv...Continue Reading

References

Jul 27, 1999·Journal of the Royal Army Medical Corps·M J RobertsL S Wong
Mar 22, 2001·Biochemistry·P B Moore
Sep 13, 2002·The New England Journal of Medicine·John MartynyLee S Newman
May 2, 2003·Pediatric Annals·Thomas R BurklowJames M Madsen
Jun 3, 2005·The European Respiratory Journal·S J Lloyd-OwenJ A Wedzicha
May 5, 2006·Journal of Intensive Care Medicine·Shannon S CarsonTimothy S Carey
Aug 2, 2007·American Journal of Public Health·Bryan L Williams, Melina S Magsumbol
May 7, 2014·Annals of Internal Medicine·Yossi RosmanMichael Kassirer

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