A child with vestibular neuritis. is adenovirus implicated?

Brain & Development
Raffaella ZannolliDaniele Nuti

Abstract

Vertigo in children is relatively under examined in the literature. Among its causes, vestibular neuritis (VN) represents only 2% of cases, with its etiology remaining unknown. We report for the first time a 4-year-old boy with vestibular neuritis and serological results compatible with adenoviral infection. Serological diagnosis was performed on the basis of a rise and consequent normalization of complement fixation (CF) titers of the plasma antibodies. Although we were not able to detect exactly when the infection started, we were able to detect an increased level of adenovirus antibodies by CF titers, followed by a decrease (i.e. 1/16, then 1/8, then <1/4) during the recovery. This is typical of a resolving infection. Furthermore, that this increase in antibodies was specific to an adenovirus infection was suggested by the observation that we did not detect increases in antibodies to other common viruses (i.e. herpes simplex and zoster viruses, Epstein-Barr virus, cytomegalovirus, influenza and parainfluenza viruses). This allows us to exclude the chance of nonspecific antibody activation. We concluded that, although our data do not formally demonstrate an involvement of adenovirus in VN, they suggest such an involvement. Th...Continue Reading

References

Jul 26, 2003·International Journal of Pediatric Otorhinolaryngology·Yun-Hoon ChoungSang Jun Ryu
Oct 19, 2004·International Journal of Pediatric Otorhinolaryngology·Hiroko Monobe, Toshihisa Murofushi

❮ Previous
Next ❯

Citations

Sep 8, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Brian F Worden, Nikolas H Blevins
Mar 29, 2014·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Jennifer B ChristyCraig Formby
Apr 9, 2011·Otolaryngologic Clinics of North America·Devin L McCaslinJill M Gruenwald
Jan 6, 2007·International Journal of Pediatric Otorhinolaryngology·Dimitrios G BalatsourasStavros G Korres
Jun 29, 2015·International Journal of Pediatric Otorhinolaryngology·Roland HülseAngela Wenzel
Sep 13, 2007·Otolaryngologia polska. The Polish otolaryngology·Katarzyna Bujak, Irena Kasacka
Oct 25, 2017·Journal of Vestibular Research : Equilibrium & Orientation·Angela WenzelRoland Hülse

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

Archives of Otolaryngology--head & Neck Surgery
C M Bower, R T Cotton
Clinical Otolaryngology and Allied Sciences
A W Blayney, B H Colman
© 2021 Meta ULC. All rights reserved