PMID: 9186790May 1, 1997Paper

A chromosome 18 genetic linkage study in three large Belgian pedigrees with bipolar disorder

Journal of Affective Disorders
S ClaesJ J Cassiman

Abstract

The contribution of genetic factors to the susceptibility for affective disorders has been firmly established. Recent reports found evidence for a susceptibility locus for affective disorders in 2 regions on chromosome 18. We describe 3 large Belgian pedigrees with multiple patients with affective disorders. Both chromosome 18 regions were investigated in the 3 families, using parametric and nonparametric segregation methods. In the pericentromeric region, all evidence was against a disease gene in our families. Also the data obtained for the distal part of 18q, argue against a genetic susceptibility factor in our sample.

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Citations

Mar 20, 2001·Bipolar Disorders·J B Potash, J R DePaulo
Jul 14, 1999·American Journal of Medical Genetics·G TureckiM Alda
Sep 22, 1999·American Journal of Medical Genetics·T BowenN Craddock
Feb 24, 2004·CNS Spectrums·Carol A Mathews, Victor I Reus

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