A circular plasmid from the yeast Torulaspora delbrueckii

Plasmid
J BlaisonneauH Fukuhara

Abstract

A new member of the 2-micron family of plasmids, named pTD1, was found in the yeast Torulaspora delbrueckii, a widespread yeast associated with food. Nucleotide sequences revealed the presence of a pair of inverted repeats and three open reading frames, one of which is a homologue of the FLP recombinase gene of 2-micron plasmid. An ARS region was identified, by replication in Saccharomyces cerevisiae and T. delbrueckii, near one of the inverted repeats. By the use of pTD1 derivatives and auxotrophic mutant hosts an efficient host-vector system was established for T. delbrueckii. So far, the 2-micron family of plasmids is restricted to four closely related genera (Q6 group): Saccharomyces, Zygosaccharomyces, Kluyveromyces, and Torulaspora. After a survey of 2500 strains belonging to about 500 species (80 genera) of yeast, no circular plasmids were found in other genera.

References

Feb 1, 1992·Journal of General Microbiology·X J ChenH Fukuhara
Aug 1, 1989·Current Genetics·X J ChenH Fukuhara
Feb 1, 1986·Journal of Bacteriology·P Sadowski
Jan 1, 1987·Methods in Enzymology·J D BoekeG R Fink
Mar 20, 1985·Journal of Molecular Biology·H ArakiY Oshima
Aug 28, 1980·Nature·J L Hartley, J E Donelson
Aug 15, 1995·FEMS Microbiology Letters·H Fukuhara

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Citations

Aug 13, 2011·Proceedings of the National Academy of Sciences of the United States of America·Aljoscha NernGerald M Rubin
Nov 19, 2009·Nucleic Acids Research·Santanu K GhoshMakkuni Jayaram
May 1, 2013·Nucleic Acids Research·Eugenia VoziyanovaYuri Voziyanov
Aug 12, 2009·Eukaryotic Cell·A Carolin Frank, Kenneth H Wolfe
Nov 12, 2015·Journal of Molecular Biology·Eugenia VoziyanovaYuri Voziyanov
Sep 22, 2009·Cell·Harmit S Malik, Steven Henikoff
Nov 5, 2016·Yeast·Cristian Varela, Anthony R Borneman
Jun 9, 2017·Genetics·Bernard A Dujon, Edward J Louis
Sep 10, 2015·Microbiology Spectrum·Makkuni JayaramYuri Voziyanov

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