A citywide protocol for primary PCI in ST-segment elevation myocardial infarction

The New England Journal of Medicine
Michel R Le MayMarino Labinaz

Abstract

If primary percutaneous coronary intervention (PCI) is performed promptly, the procedure is superior to fibrinolysis in restoring flow to the infarct-related artery in patients with ST-segment elevation myocardial infarction. The benchmark for a timely PCI intervention has become a door-to-balloon time of less than 90 minutes. Whether regional strategies can be developed to achieve this goal is uncertain. We developed an integrated-metropolitan-area approach in which all patients with ST-segment elevation myocardial infarction were referred to a specialized center for primary PCI. We sought to determine whether there was a difference in door-to-balloon times between patients who were referred directly from the field by paramedics trained in the interpretation of electrocardiograms and patients who were referred by emergency department physicians. Between May 1, 2005, and April 30, 2006, a total of 344 consecutive patients with ST-segment elevation myocardial infarction were referred for primary PCI: 135 directly from the field and 209 from emergency departments. Primary PCI was performed in 93.6% of patients. The median door-to-balloon time was shorter in patients referred from the field (69 minutes; interquartile range, 43 to ...Continue Reading

References

Apr 4, 1985·The New England Journal of Medicine·UNKNOWN TIMI Study Group
Dec 8, 2000·Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology·G Bernardi
Feb 1, 2003·European Heart Journal·Frans Van de WerfUNKNOWN Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology
Aug 22, 2003·The New England Journal of Medicine·Henning R AndersenUNKNOWN DANAMI-2 Investigators
Feb 24, 2006·Circulation·Elizabeth H BradleyHarlan M Krumholz
Mar 8, 2006·The Canadian Journal of Cardiology·Marino LabinazUNKNOWN CCN Consensus Panel on Access to Urgent PCI for ST Segment Elevation Myocardial Infarction
Jun 6, 2006·Journal of the American College of Cardiology·Robert L McNamaraUNKNOWN NRMI Investigators
Nov 15, 2006·The New England Journal of Medicine·Elizabeth H BradleyHarlan M Krumholz

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Citations

Apr 24, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Birga MaierHeinz P Theres
Jul 1, 2010·Cardiovascular Intervention and Therapeutics·Kazuo KimuraJyun Okuda
Jul 24, 2010·JACC. Cardiovascular Interventions·Hendrik-Jan DiekerFreek W A Verheugt
Jul 24, 2010·JACC. Cardiovascular Interventions·Alice K Jacobs, Claudia P Hochberg
Dec 22, 2012·Prehospital and Disaster Medicine·Amado Alejandro BáezSusan R Wilcox
Sep 18, 2008·Nature Clinical Practice. Cardiovascular Medicine·Keith A A Fox, Kurt Huber
Apr 19, 2008·The New England Journal of Medicine·Peter Bogaty, James M Brophy
Sep 16, 2011·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Natale Daniele BrunettiMatteo Di Biase
Aug 28, 2012·European Heart Journal·UNKNOWN Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)Doron Zahger
Apr 19, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Christopher R CarpenterDouglas K Miller
Jul 29, 2010·Circulation. Cardiovascular Quality and Outcomes·Thomas W ConcannonHarry P Selker
Sep 30, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Michel Le May
Jul 1, 2008·Future Cardiology·Rik Hermanides, Jan Paul Ottervanger
Jul 19, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Paolo OrtolaniAngelo Branzi
Aug 24, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Rasmus HesselfeldtLars S Rasmussen
Aug 24, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Miles DalbyUNKNOWN Member of the College of Paramedics
Jan 1, 2012·Global Cardiology Science & Practice·Abdurrazzak GehaniMagdi Yacoub
Jul 31, 2012·Cardiology Research and Practice·Sofia-Iris BibliTheofilos M Kolettis
Mar 29, 2014·Current Treatment Options in Cardiovascular Medicine·Vikas Singh, Mauricio G Cohen
Dec 29, 2011·Emergency Medicine International·Stephen H Thomas, Annette O Arthur
Aug 22, 2008·Current Cardiology Reports·David M Larson, Timothy D Henry
Jun 28, 2008·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Michael G MillinTom P Aufderheide
Jan 5, 2016·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Sae Won ChoiEui Jung Lee
Dec 4, 2014·International Journal of Cardiology·Ashlay A HuitemaShahar Lavi
Jun 30, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoichi ImoriShigeru Saito
May 28, 2013·The American Journal of Emergency Medicine·Ryan E WilsonLyndon C Box
Apr 30, 2014·Revista Española De Cardiología·Jacob Thorsted SørensenMaria Sejersten
Sep 27, 2012·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Nuno MarquesIlídio Jesus
Sep 18, 2012·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Pedro Jerónimo SousaMiguel Mendes
May 10, 2011·JEMS : a Journal of Emergency Medical Services·Christopher KrallBryan Bledsoe

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