A clinical and etiologic profile of spastic diplegia

Pediatric Neurology
Richard Tang-WaiMichael Shevell

Abstract

To identify the clinical and etiologic profile of children with spastic diplegia, the medical records of patients with spastic diplegia in a single practice over a 12-year period were systematically and retrospectively reviewed. Clinical factors and possible etiology based on investigations were identified. Univariate and binomial logistical regression analyses were undertaken to identify factors correlating with an etiologic determination. Chart review identified 54 children with spastic diplegia. There were 31 (57.4%) preterm children and 23 (42.6%) term children. Periventricular leukomalacia was diagnosed in 24 (44.4%) children (26.1% of term children, 58.1% of preterm children). An etiology was not identified in 25 (46.3%) children: 14 (60.9%) term children and 11 (35.5%) preterm children. Periventricular leukomalacia among all children correlated with a birth weight less than 2000 gm (P = 0.037), history of neonatal resuscitation (P = 0.004), and gestation less than 33 weeks (P = 0.001). Factors specifically associated with periventricular leukomalacia in term children were a problematic perinatal history (P = 0.011), a history of neonatal resuscitation (P = 0.011), and a history of neonatal respiratory distress (P = 0.046...Continue Reading

References

Nov 1, 1988·Child: Care, Health and Development·N J WildP R Dear
Jan 20, 1994·The New England Journal of Medicine·K C Kuban, A Leviton
Feb 1, 1996·Acta Paediatrica Japonica; Overseas Edition·M KubotaA Nishida
Oct 6, 2000·Pediatric Neurology·S P MillerA M O'Gorman
Jul 2, 2003·European Radiology·Alessandro BozzaoRoberto Floris
Jul 25, 2003·Pediatric Neurology·Michael I ShevellIsabelle Morin
Dec 1, 1963·Archives of Disease in Childhood·A D MCDONALD

❮ Previous
Next ❯

Citations

Jan 17, 2012·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M BourrousM Bouskraoui
Sep 4, 2007·Pediatric Neurology·Sunita Venkateswaran, Michael I Shevell
Feb 24, 2015·Archives of Disease in Childhood·Richard HuntsmanSimona Hasal
Feb 22, 2018·Journal of Child Neurology·Prashant JauhariNiranjan Khandelwal
Jan 18, 2008·Pró-fono : revista de atualização científica·Dionísia Aparecida Cusin Lamônica, Plínio Marcos Duarte Pinto Ferraz
Sep 25, 2018·Journal of Back and Musculoskeletal Rehabilitation·Walaa Abd El-Hakiem Abd El-Nabie, Marwa Shafiek Mustafa Saleh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.