A clinical and optical coherence tomography study of choroidal colobomas

Current Opinion in Ophthalmology
L Gopal

Abstract

This paper reviews current understanding of coloboma of the choroid, as evaluated clinically and using optical coherence tomography. Studies of the margin of coloboma of the choroid with optical coherence tomography revealed several interesting features, including variability in transition from normal retina to intercalary membrane (gradual or abrupt), presence of subclinical retinal detachments, focal communications between the subretinal space and subintercalary membrane space in eyes with extra-colobomatous retinal detachments, and inward humping of the eye wall in some cases. Pathological studies have stressed the importance of the intercalary membrane and the margin of coloboma as barriers for occurrence of retinal detachments. Vitrectomy and silicone oil tamponade could correct these retinal detachments in a majority of cases. Optical coherence tomography can provide insight into pathology at the margin of the coloboma. Coupled with knowledge from histopathological studies, this information can guide the management of retinal detachments secondary to coloboma of the choroid with a high degree of success.

References

Jan 1, 1992·Retina·B CorcosteguiJ García-Arumí
Nov 1, 1991·Ophthalmology·L GopalT Sharma
Mar 15, 1991·American Journal of Ophthalmology·A HannekenB W McCuen
Apr 1, 1970·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·R J Schneider
Jun 1, 1969·American Journal of Ophthalmology·J D Gass
Jan 1, 1981·Survey of Ophthalmology·R A Pagon
Feb 1, 1995·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·H D Schubert
Jun 26, 1998·The British Journal of Ophthalmology·H Lincoff, I Kreissig
Jul 8, 1998·Retina·J MoisseievG Treister
Nov 30, 2000·Survey of Ophthalmology·B C OnwocheiE Mir
Aug 14, 2001·Archives of Ophthalmology·A GuptaP Singh
Sep 11, 2002·European Journal of Ophthalmology·N UnlüS Duman
Dec 1, 1960·Archives of Ophthalmology·E W KRANENBURG
Feb 1, 1961·Archives of Ophthalmology·D O JESBERG, C L SCHEPENS
Apr 23, 2004·Ophthalmology Clinics of North America·Irene VooCarmen A Puliafito
Oct 13, 2004·Archives of Ophthalmology·Francesco ViolaGiovanni Staurenghi
Dec 14, 2004·Journal of Medical Genetics·C Y Gregory-EvansK Gregory-Evans
Dec 15, 2004·Archives of Ophthalmology·T Mark Johnson, Mark W Johnson
Dec 22, 2004·Journal of Pediatric Ophthalmology and Strabismus·Michelle S YingDennis M Marcus
Jan 22, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rodrigo Luz MeirellesMichel Eid Farah
Jun 14, 2006·Indian Journal of Ophthalmology·Nikhil PalYog Raj Sharma
Aug 26, 2006·Current Opinion in Ophthalmology·Lan ChangBrian P Brooks
Nov 25, 2006·Ophthalmology·Lingam GopalVilakkumadadhil S Prakash
Feb 20, 2007·Klinische Monatsblätter für Augenheilkunde·J von EickenK Rehfeldt
Jun 5, 2007·Journal of Pediatric Ophthalmology and Strabismus·Zia ChaudhuriSanjiv Mohan

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Citations

Nov 3, 2016·Veterinary Ophthalmology·Elisa M Gonzalez-Alonso-AlegreJavier Esteban-Martín
Jun 27, 2018·Indian Journal of Ophthalmology·Jorge Ruiz-MedranoJose M Ruiz-Moreno
Aug 9, 2017·BMJ Case Reports·Brijesh TakkarMeghal Gagrani
Dec 9, 2010·International Ophthalmology Clinics·Benjamin NicholsonJonathan E Sears
Apr 3, 2020·Health Policy and Planning·Yuvaraj KrishnamoorthySathish Rajaa
Oct 30, 2016·European Journal of Ophthalmology·Luisa PierroFrancesco Bandello
Sep 10, 2021·Seminars in Ophthalmology·Sushma JayannaJay Chhablani

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