PMID: 7017171Jun 1, 1981Paper

A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection

The Journal of Urology
J G Bucy

Abstract

In a single blind clinical study of 50 patients with urinary tract infections 250 mg. cinoxacin were compared to 1 g. nalidixic acid 4 times daily. Both drugs produced similar improvement in symptomatic response during therapy and were equally effective in eradicating the causative pathogens. In the 5 of 9-day post-therapy followup 4 patients from the cinoxacin group became reinfected compared to 1 from the nalidixic acid group. Side effects were reported by twice as many patients in the nalidixic acid group. It is concluded that cinoxacin is an effective drug for the treatment of uncomplicated urinary tract infections.

References

Feb 1, 1979·Antimicrobial Agents and Chemotherapy·H R BlackJ D Wolny
May 1, 1975·Antimicrobial Agents and Chemotherapy·H Giamarellou, G G Jackson

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Citations

Jul 21, 2006·The Cochrane Database of Systematic Reviews·V RafalskyE Rjabkova
Dec 1, 1982·Drug Intelligence & Clinical Pharmacy·D R Guay

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