A clinical comparison of tobramycin and gentamicin sulfate in the treatment of ocular infections

American Journal of Ophthalmology
P LaibsonG Cagle

Abstract

We evaluated the safety and efficacy of tobramycin and gentamicin sulfate ophthalmic solutions in the treatment of patients with bacterial infections of the conjunctivas. In this double-masked study involving 66 patients, the two aminoglycosides were found to be equally safe and effective, although the in vitro data suggested that tobramycin may be more efficacious against Pseudomonas infections. Staphylococcus aureus and S. epidermidis were the most frequent isolates from the infected eyes (59.8% and 20.6%, respectively).

References

Sep 1, 1977·Archives of Ophthalmology·S D DavisR A Hyndiuk
Apr 1, 1974·American Journal of Ophthalmology·G SmolinF M Wilson
Jan 1, 1974·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·T O Bennett, G A Peyman
Aug 1, 1972·The Journal of Clinical Pharmacology and New Drugs·B R Meyers, S Z Hirschman
Jan 1, 1972·Antimicrobial Agents and Chemotherapy·J Dienstag, H C Neu
Mar 1, 1980·The Journal of Infectious Diseases·R A WeinsteinS A Kabins

❮ Previous
Next ❯

Citations

Jun 15, 1991·American Journal of Ophthalmology·C R DavisonJ K Dart
Aug 15, 1988·American Journal of Ophthalmology·L R Borrmann, I H Leopold
Mar 8, 2003·Ophthalmology·Ivan R SchwabUNKNOWN Levofloxacin Bacterial Conjunctivitis Active Control Study Group
Jan 10, 2017·The Cochrane Database of Systematic Reviews·Kristina LindsleyKay Dickersin
Mar 1, 1989·Current Eye Research·J H LassH M Lazarus
Oct 13, 2007·European Journal of Ophthalmology·F I CamesascaUNKNOWN Italian Betamethasone-Chloramphenicol vs Dexamethasone-Tobramycin Combination Study Group
Sep 1, 1987·Survey of Ophthalmology·K R WilhelmusM S Osato

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.