A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal.

Lasers in Medical Science
Semra Akinturk, Ahmet Eroglu

Abstract

The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers. Fifty female volunteers were enrolled in this prospective, randomized, double-blind, clinical study over a 6-month period. Patients were randomly assigned to receive topical piroxicam as group Piroxicam or EMLA cream as group EMLA. Topical analgesics were applied to the treatment sites for 60 min. The pain scores [on a visual analog scale (VAS)] and side effects were recorded before the hair removal, during the hair removal, at the end of the hair removal, and 1 h, 2 h and 24 h after the hair removal. Patients' characteristics and the treatment settings of the Nd:YAG 1,064 nm laser were similar in the two groups. The pain scores (VAS) were similar, and satisfaction was high in both groups after the hair removal. The number of blanching and erythema episodes were significantly higher in group E than in group P (P < 0.001). Inflammatory side effects were less frequent in group P than in group E after the procedure (P < 0.001). This study showed that topical piroxicam and EMLA provided adequate and similar pa...Continue Reading

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Citations

May 8, 2014·Advanced Biomedical Research·Ali AsilianMohammad Ali Nilforoushzadeh
Nov 22, 2015·Journal of Cosmetic Dermatology·Jean-Marc Aimonetti, Edith Ribot-Ciscar
Nov 20, 2012·Dermatologic Clinics·Soodabeh Zandi, Harvey Lui
Jan 21, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·K GrevelingM B A van Doorn
Aug 16, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ahmed M AbbasAhmed Samy
Jun 21, 2018·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Shannon Humphrey, Alastair Carruthers

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