A clinical guideline on Dientamoeba fragilis infections

Parasitology
Rosanne Sfe van GestelJan F Monkelbaan

Abstract

Dientamoeba fragilis (D. fragilis) is an intestinal parasite frequently detected in humans with abdominal pain and diarrhoea, but it is also commonly found in asymptomatic subjects. Hence its clinical relevance is often disputed. The introduction of polymerase chain reaction (PCR) is a versatile and sensitive diagnostic technique for the detection of intestinal parasites, and in some Western world countries PCR has almost completely replaced microscopic diagnostics. PCR has however resulted in an increase in the number of D. fragilis-positive patients. The disputed pathogenic nature of this intestinal parasite and an apparent increase in the incidence of patients with positive PCR results have renewed the discussions between clinicians and microbiologists on how to deal with an infected patient. Moreover, treatment guidelines differ throughout the world which makes it difficult for clinicians to choose an optimal therapeutic regimen.AimTo summarize and discuss the current knowledge on the pathogenicity, best diagnostic approach, treatment and follow-up of children and adults infected with D. fragilis.

References

Apr 1, 1979·American Journal of Diseases of Children·M J SpencerM R Chapin
Jan 1, 1977·The American Journal of Tropical Medicine and Hygiene·J Yang, T Scholten
Jun 1, 1989·Biochemical Society Transactions·C A HartJ R Saunders
Sep 1, 1966·The American Journal of Digestive Diseases·B H Kean, C L Malloch
Apr 1, 1983·Digestive Diseases and Sciences·V MilletL S Garcia
Dec 1, 1983·Digestive Diseases and Sciences·J Rask-MadsenR Henrik-Nielsen
Jan 1, 1983·The American Journal of Tropical Medicine and Hygiene·V E MilletM E Stewart
Feb 1, 1995·Molecular Ecology·M C Silva, C A Batt
Sep 1, 1996·Digestive Diseases and Sciences·W P Butler
Dec 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F ChanA Mackenzie
Jan 27, 1998·Journal of Pediatric Gastroenterology and Nutrition·C CuffariE G Seidman
Dec 2, 2000·Journal of Clinical Microbiology·J A Johnson, C G Clark
Mar 27, 2001·Emerging Infectious Diseases·M A de WitY T van Duynhoven
Jan 10, 2002·The American Journal of Emergency Medicine·Eva C DickinsonMelissa K Schlenker
Mar 16, 2002·Journal of Gastroenterology and Hepatology·L D Chitti, I C Roberts-Thomson
May 2, 2002·Journal of Gastroenterology and Hepatology·Roy M Robins-Browne, Elizabeth L Hartland
Feb 18, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·N GirginkardeşlerU Z Ok
Apr 15, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A NorbergB Evengård
May 9, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T van GoolT G Mank
Feb 10, 2004·Journal of Clinical Microbiology·Ron PeekTom van Gool
Feb 14, 2006·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Olivier VandenbergTom van Gool
May 9, 2006·The Journal of Eukaryotic Microbiology·Jeffrey J WindsorC Graham Clark
Aug 31, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Philippe R Lagacé-WiensCliff Koschik
Jan 2, 2007·The Pediatric Infectious Disease Journal·Olivier VandenbergTom van Gool
Jun 26, 2007·Molecular and Cellular Probes·Jaco J VerweijLisette van Lieshout
Oct 9, 2007·Parasitology International·Nogay GirginkardeşlerUlgen Z Ok
Apr 10, 2008·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·O KurtU Z Ok
Jul 25, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L E S Bruijnesteijn van CoppenraetJ J Verweij
Feb 16, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D StarkJ Ellis
Mar 30, 2010·The American Journal of Tropical Medicine and Hygiene·Damien StarkJohn Ellis
May 14, 2010·Diagnostic Microbiology and Infectious Disease·Adriana CalderaroCarlo Chezzi
Jan 29, 2011·Acta Paediatrica·C F M GijsbersHa Büller
Oct 26, 2011·Antimicrobial Agents and Chemotherapy·N NagataD Stark
Feb 4, 2012·The American Journal of Tropical Medicine and Hygiene·Damien StarkJohn T Ellis
Apr 21, 2012·Emerging Infectious Diseases·Simone M CacciòEdoardo Pozio
Nov 30, 2012·The Pediatric Infectious Disease Journal·Janna M A Ter SchureTina E Faber
Feb 27, 2013·Revista brasileira de anestesiologia·Necla DereliFiliz Koç
Apr 24, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D RöserK Mølbak
Jul 23, 2013·International Journal for Parasitology·Varuni S MunasingheDamien Stark
Oct 18, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L MaasB E van Ewijk

❮ Previous
Next ❯

Citations

May 6, 2019·Journal of Medical Microbiology·Jari IntraPaolo Brambilla
Mar 11, 2020·Expert Review of Gastroenterology & Hepatology·Michael W van KalleveenFrans B Plötz
Dec 20, 2020·European Journal of Protistology·Maria Cristina AngeliciJoel B Dacks

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Bulletin de la Société de pathologie exotique et de ses filiales
L LAMY
Bulletin de la Société de pathologie exotique et de ses filiales
K AddadiA Tabet-Derraz
Journal of the American Medical Association
M A SWERDLOW, R B BURROWS
© 2022 Meta ULC. All rights reserved